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KMID : 0861020100250030091
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Korea Journal of Herbology
2010 Volume.25 No. 3 p.91 ~ p.95
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Effects of Acori Rhizoma Extract on the in vitro Anti-platelet Activity in Human Whole Blood
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Choi Go-Ya
Kim Seul-Ki
Lee In-Sun
Baek Ji-Seong
Jeon Won-Kyung
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Abstract
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Objectives : Acori Rhizoma is one of the common widely used herbal medicines with diverse bioactive effects. However, little evidence has been reported about the potential anti-platelet activity of Acori Rhizoma. The present study examined the effects on platelet aggregation by Acori Rhizoma.
Methods : In this study, we tested the in vitro effect of 16 kinds of Acori Rhizoma extracts by hot water or 70% ethanol on collagen-induced platelet aggregation in human whole blood using the impedance method of aggregometry.
Results : Among them, 2 kinds of 70% ethanol extract and 1 kind of hot water extract showed the significant inhibiting effect on whole blood aggregation. In particular, Acorus gramineus extracts were selected as the most effective candidate.
Conclusiions : The results from this experiment provide pharmacological evidence for the traditional medicine, suggesting that Acorus gramineus could be help problems of blood circulation more than Acorus tatarinowii.
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KEYWORD
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Acori Rhizoma, platelet aggregation, Acorus gramineus, Acorus tatarinowii
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